Explore the Science Behind Regenerative Matrix Therapy™
We believe in transparency, evidence, and continuous learning.
This is where we share the science that shapes our protocol and the insights that guide our work.
Regenerative Matrix Therapy™ is grounded in biology and guided by research. This page is updated regularly with original educational content that relates to our treatment philosophy, as well as summaries of published clinical studies and peer-reviewed trials on treatments that share foundational similarities with our approach.
While many of the featured studies reflect the growing body of evidence supporting biologic and regenerative therapies, Regenerative Matrix Therapy™ is built upon and enhanced from this foundation — representing a next-generation application designed with precision, personalization, and performance in mind.
Each article is written to make the data understandable and relevant — for both physicians and curious patients — while maintaining scientific accuracy and integrity.
2018 Study: Adipose Therapy Helped in Severe Knee Osteoarthritis (OA)
A 2018 Study showed a single adipose injection for “bone-on-bone” severe knee OA reduced pain and boosted function at 12 months, with no serious adverse events.
2020 Study: Adipose Injection Helped Mild-to-Moderate Shoulder OA
2020 study: a single adipose (fat) injection led to ~80–90% pain relief and strong functional gains in mild-to-moderate shoulder OA at 1 year.
Evidence Summary: Adipose Therapy Provides Durable Relief for Partial Rotator Cuff Tears Without Surgery
Evidence summary of adipose-based therapy for partial thickness rotator cuff tears: ~50% better function, up to 80% less pain, and 3-year durability.
Wrist Osteoarthritis (OA) Evidence Summary: Adipose Therapy Shows Durable Relief
Multi-study evidence shows adipose therapy can cut wrist OA pain by over 50%, improve function and grip, with quick recovery and relief lasting over 1 year.
2020 Trial: Adipose Injection Helped Even in Severe Knee Osteoarthritis (OA)
A 2020 clinical study followed patients – most with advanced disease – after a single, ultrasound-guided injection prepared from their own fat or adipose tissue and reported meaningful improvements in pain, function, and quality of life over 12 months.
2019 Trial: Adipose Therapy Significantly Reduces Pain and Shows New Cartilage Signal in Knee Osteoarthritis (OA)
A 2019 clinical trial followed patients for two years after a single injection of adipose (fat) tissue and found MRI signals consistent with improved cartilage composition alongside dramatic reductions in pain.